Why the study?
Does transvenous left ventricular lead implantation maintain stable pacing parameters and safety over long-term follow-up in patients requiring CRT or pacemakers?
Does transvenous left ventricular lead implantation maintain stable pacing parameters and safety over long-term follow-up in patients requiring CRT or pacemakers?
Transvenous left ventricular leads demonstrate stable pacing parameters and a low rate of serious complications over a 2-year follow-up period.
Supports 2-year stability of transvenous LV leads in CRT; hypothesis-generating and should not yet change practice.
Transvenous left ventricular (LV) lead implantation is on the increase due to cardiac resynchronization therapy (CRT). However, there has been paucity of data on the prognosis of LV lead. Consecutive 32 patients with LV lead for CRT (n=22) or pacemaker (n=10) were subjected. Serial changes in pacing threshold and impedance along with lead-related complications were evaluated. Over 2 yr follow-up, there was no significant change in relative threshold voltage to the initial value (100%, 110%, 89.6%, and 79.6% at baseline, 1, 6, and 24 months respectively, P=0.62) as well as lead impedance (816±272, 650±178, 647±191, and 590±185 ohm at baseline, 1, 6, and 24 months respectively, P=0.80). The threshold change was not affected by lead position, lead polarity, and indication of lead implantation. The cumulative rates of lead revision were 6.3% (n=2) and 9.4% (n=3) in 6 month and 2 yr follow-up, respectively. One case of phrenic nerve capture at left lateral decubitus position was detected 1 month after the implantation. However, there were no serious complications over 2 yr period. In conclusion, transvenous LV lead implantation showed favorable long-term prognosis. Pacing parameters remained stable without significant changes over 2 yr follow-up.
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Park et al. (2010) studied this question.
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