Why the study?
Does oral mexiletine or disopyramide suppress recurrent sustained ventricular tachycardia in patients with previously drug-resistant tachycardias?
Population
34 patients with recurrent sustained ventricular tachycardias. Underlying conditions included coronary heart…
Design
Cohort
Follow-up
mean 24 months
Authors
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Low VT suppression with mexiletine or disopyramide in resistant cases; leaves open optimal strategies pending prospective trials.
Does oral mexiletine or disopyramide suppress recurrent sustained ventricular tachycardia in patients with previously drug-resistant tachycardias?
Mexiletine and disopyramide achieve complete suppression of ventricular tachycardia in only a small minority of patients with previously drug-resistant tachycardias.
Manz et al. (1983) studied this question.
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