Why the study?
Does tempol reduce the exaggerated muscle reflex in rats with heart failure?
Does tempol reduce the exaggerated muscle reflex in rats with heart failure?
Excess superoxide contributes to the exaggerated muscle reflex in heart failure, which can be attenuated by the superoxide dismutase mimetic tempol.
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Tempol attenuates exaggerated muscle reflex in MI rats; leaves open superoxide-targeted therapies for human HF.
Koba et al. (2009) studied this question.
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