Key result
The BUDAPEST-GLOBAL study is a prospective, single-center twin study designed to evaluate the genetic and environmental influences on coronary atherosclerotic plaque burden.
Why the study?
What is the influence of genetic and environmental factors on the burden of coronary artery disease as assessed by CT imaging in twins?
Population
202 twins enrolled from the Hungarian Twin Registry database
Comparison
Non-contrast-enhanced computed tomography and… vs Comparison between monozygotic and dizygotic…
Design
Cohort
Authors
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Twin design may partition genetic versus environmental plaque influences; leaves open causal inferences and practice change.
Observational (n=202)
No
What is the influence of genetic and environmental factors on the burden of coronary artery disease as assessed by CT imaging in twins?
The BUDAPEST-GLOBAL study provides a framework to evaluate the genetic and environmental influences on coronary artery disease burden and cardiometabolic disorders using advanced CT imaging in twins.
Maurovich‐Horvat et al. (2015) conducted an observational in Coronary artery disease (n=202). Genetic and environmental factors was evaluated on Presence and volume of atherosclerotic plaques. The BUDAPEST-GLOBAL study is a prospective, single-center twin study designed to evaluate the genetic and environmental influences on coronary atherosclerotic plaque burden.
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