Key result
Colchicine is highlighted as a promising therapeutic agent for cardiovascular diseases, including atrial fibrillation, ischemic cardiopathy, and pericarditis, with improving tolerability profiles.
Colchicine is highlighted as a promising therapeutic agent with pleiotropic anti-inflammatory effects for cardiovascular diseases including atrial fibrillation, ischemic cardiopathy, and pericarditis.
May support colchicine evaluation in AF and pericarditis; leaves open confirmation by randomized trials before practice change.
Colchicine is a venerable drug used for centuries for rheumatic diseases with potential pleiotropic anti-inflammatory effects. One of the main concerns remains the tolerability especially digestive side effects, but this aspect has been improved by many pharmacological improvements. Nowadays, colchine is a promising drug for cancer therapy and cardiovascular diseases with several studies currently going on, an improved therapeutic window and a wider range of translations in cardioprotection but also in atrial fibrillation, ischemic cardiopathy or pericarditis.
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Lattuca et al. (2015) conducted a review in Cardiovascular diseases. Colchicine was evaluated. Colchicine is highlighted as a promising therapeutic agent for cardiovascular diseases, including atrial fibrillation, ischemic cardiopathy, and pericarditis, with improving tolerability profiles.
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