Key result
Ambulatory monitoring in healthy volunteers showed significant diurnal fluctuations, with afternoon heart rate and LF/HF ratio increasing by 23.6% and 69.1% compared to nighttime (P<0.001).
Observational (n=61)
p-value: p=<.001
Continuous ambulatory monitoring in healthy volunteers demonstrates significant diurnal fluctuations in heart rate variability, with peaks in sympathetic tone during the afternoon and upon waking.
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Time-of-day effects may confound single-point HRV measures; leaves open whether adjustment improves prognostic utility in patients.
Kim et al. (2014) conducted an observational in Healthy volunteers (n=61). Continuous ambulatory HRV monitoring was evaluated on Diurnal fluctuations of HR and LF/HF ratio (p=<.001). Ambulatory monitoring in healthy volunteers showed significant diurnal fluctuations, with afternoon heart rate and LF/HF ratio increasing by 23.6% and 69.1% compared to nighttime (P<0.001).
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