Why the study?
Do beta-blocking agents with and without intrinsic sympathomimetic activity improve work efficiency in healthy men?
Population
7 healthy men
Comparison
Propranolol 80 mg oral twice daily and pindolol… vs Placebo
Design
RCT, randomized, cross-over fashion, double-blind
Follow-up
7 days
Authors
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Enhances submaximal exercise efficiency in healthy men; extends evidence for beta blocker effects independent of intrinsic sympathomimetic activity.
Do beta-blocking agents with and without intrinsic sympathomimetic activity improve work efficiency in healthy men?
Propranolol and pindolol increase the efficiency of submaximal work in healthy men, allowing external work to be performed with lower oxygen consumption.
Mäki et al. (1996) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: