Why the study?
Does renal hypertension alter the baroreceptor-heart rate reflex in unanaesthetized rabbits?
Population
21 renal hypertensive and 28 normotensive unanaesthetized rabbits (n=49)
Comparison
Variation of intravascular pressures by… vs Normotensive unanaesthetized rabbits
Design
Preclinical
Authors
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Baroreflex resetting and blunting accompany renal hypertension in rabbits; leaves open whether these changes are nonspecific consequences in human essential hypertension.
Does renal hypertension alter the baroreceptor-heart rate reflex in unanaesthetized rabbits?
Renal hypertension in rabbits produces baroreflex changes similar to those in human essential hypertension, suggesting these changes are non-specific accompaniments of chronic blood pressure elevation.
West et al. (1974) studied this question.
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