Key result
Endothelial dysfunction in heart failure has significant prognostic value and varies by aetiology, though its clinical application is hampered by methodological limitations.
Population
Patients with heart failure (including ischemic and non-ischemic etiologies)
Design
Review
Authors
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May refine HF prognostication by aetiology; leaves open standardized measures and targeted therapies.
Endothelial dysfunction plays a significant pathophysiological and prognostic role in heart failure, varying by etiology, but lacks specific targeted therapies.
Shantsila et al. (2012) conducted a review in Heart failure. Endothelial dysfunction was evaluated. Endothelial dysfunction in heart failure has significant prognostic value and varies by aetiology, though its clinical application is hampered by methodological limitations.