March 1, 1997Clinical PhysiologyOpen Access

Validation of the acetylene rebreathing method for measurement of cardiac output at rest and during high‐intensity exercise

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Why the study?

Is the acetylene rebreathing method valid for measuring cardiac output during high-intensity exercise compared to the direct Fick method?

Population

9 subjects

Comparison

Acetylene rebreathing method for measurement of… vs Direct Fick method

Design

Other

Authors

YLY. LiuUniversität Ulm EMElmar MenoldUniversity of South Wales ADAlexander DullenkopfAnesthesia Quality Institute

Discussion

Member takes

Implication

Acetylene rebreathing agrees closely with direct Fick during high-intensity exercise; extends validation to this setting but leaves open clinical adoption pending larger studies.

Structured PICO

Is the acetylene rebreathing method valid for measuring cardiac output during high-intensity exercise compared to the direct Fick method?

Population

9 subjects

Intervention

Acetylene rebreathing method for measurement of cardiac output at rest and during exercise (25%, 50%, 75%, and 90% of VO2max)

Comparator

Direct Fick method

Outcome

Cardiac output (CO) correlation and difference between methodssurrogate

The acetylene rebreathing method is a valid alternative to the direct Fick method for measuring cardiac output during high-intensity exercise.

Cite This Study

Liu et al. (1997) studied this question.

synapsesocial.com/papers/6a7a16724353fbf060021397 https://doi.org/10.1046/j.1365-2281.1997.02323.x

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Implication

Acetylene rebreathing agrees closely with direct Fick during high-intensity exercise; extends validation to this setting but leaves open clinical adoption pending larger studies.