Why the study?
Does physical training improve QTc dispersion and reduce ventricular tachycardia in patients with nonischemic heart failure?
Does physical training improve QTc dispersion and reduce ventricular tachycardia in patients with nonischemic heart failure?
A 3-week physical training program significantly improved exercise tolerance and reduced resting QTc dispersion in patients with nonischemic heart failure, suggesting potential benefits for autonomic tone and ventricular repolarization.
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Physical training was associated with reduced QTc dispersion in nonischemic HF; hypothesis-generating for arrhythmia or outcome effects.
BACKGROUND: The effect of physical training (PT) on QTc dispersion and ventricular tachycardia (VT) remains unclear in patients with nonischemic heart failure. METHODS AND RESULTS: Eight patients with nonischemic heart failure performed PT using a bicycle ergometer and their exercise tolerance increased (4.9+/-1.8 to 7.0+/-2.5 METs, p<0.05) and QTc dispersion decreased (71+/-22 to 48+/-24 ms, p<0.05). However, PT did not change the frequency of VT. CONCLUSION: Physical training could improve QTc dispersion in patients with nonischemic heart failure, possibly by improving the autonomic nerve system.
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Nishiyama et al. (2004) studied this question.
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