Key result
Exosomes and their bioengineered modifications show promise as therapeutic vectors for targeted drug administration in central nervous system diseases due to their ability to cross the blood-brain barrier.
Why the study?
Most medications used to treat or prevent chronic central nervous system diseases cannot cross the blood-brain barrier to reach their intended target.
Design
Review
Authors
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Exosome delivery may enable CNS targeting across the BBB; leaves open clinical efficacy and safety in neurological disease.
Exosomes hold potential as therapeutic vectors for central nervous system diseases due to their ability to cross the blood-brain barrier and carry a wide range of substances.
Khan et al. (2022) conducted a review in Central nervous system diseases. Exosomes / Extracellular Vesicles was evaluated. Exosomes and their bioengineered modifications show promise as therapeutic vectors for targeted drug administration in central nervous system diseases due to their ability to cross the blood-brain barrier.
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