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Discuss the potential of exosome-based nanomedicine in treating neurological disorders with a focus on mechanisms and engineering strategies.

Exosome-based nanomedicine for neurological disorders: mechanisms, engineering, and therapeutic potential

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Review highlights exosome engineering and therapeutic delivery mechanisms for neurological disorders, suggesting novel clinical pathways.

Discuss the potential of exosome-based nanomedicine in treating neurological disorders with a focus on mechanisms and engineering strategies.
Reviewed recent advances in exosome biology and therapy.
Evaluated exosome applications in neurodegenerative diseases, stroke, and other neurological conditions.
Synthesized findings from literature searches and manual reference lists.
Engineered exosomes can effectively cross the blood-brain barrier for targeted delivery.
Identified barriers to clinical application include heterogeneity and regulatory challenges.
Provided a framework for the design and implementation of exosome-based therapies.

Singh et al. (2026) studied this question.

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