Key result
Enhanced external counterpulsation significantly increased coronary flow reserve and flow-mediated dilatation, and decreased hsCRP compared to medical therapy alone (p < 0.001).
Why the study?
Does enhanced external counterpulsation improve coronary flow, endothelial function, and inflammation in patients with coronary slow flow?
Population
45 patients with documented coronary slow flow (CSF)
Comparison
Enhanced external counterpulsation consisting of… vs Medical therapy alone
Design
Cohort, nonrandomly assigned
Follow-up
6 months
Authors
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Associated with improved coronary flow reserve and endothelial function in slow flow; hypothesis-generating, needs randomized confirmation before practice change.
Does enhanced external counterpulsation improve coronary flow, endothelial function, and inflammation in patients with coronary slow flow?
p-value: p=<0.001
Enhanced external counterpulsation provides durable improvement in coronary flow, endothelial function, and inflammation in patients with coronary slow flow.
Luo et al. (2012) studied coronary slow flow (n=45). Enhanced external counterpulsation (EECP) vs. Medical therapy alone was evaluated on Coronary diastolic peak flow velocity (DPFV), coronary flow reserve (CFR), flow-mediated dilatation (FMD), and high-sensitivity C-reactive protein (hsCRP) (p=<0.001). Enhanced external counterpulsation significantly increased coronary flow reserve and flow-mediated dilatation, and decreased hsCRP compared to medical therapy alone (p < 0.001).
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