Key result
A nonparametric frequency-domain closed-loop identification method was demonstrated for analyzing the dynamic characteristics of the arterial baroreflex system.
Why the study?
Closed-loop negative feedback operation makes it difficult to identify open-loop dynamic characteristics of the neural and peripheral arcs in the arterial baroreflex system.
A nonparametric frequency-domain closed-loop identification method can be used to estimate the open-loop dynamic characteristics of the arterial baroreflex system in an anesthetized rabbit model.
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Identifies baroreflex arc dynamics in sympathetic AP control; leaves open translation to human hypertension therapies.
Kawada et al. (2021) studied this question. Closed-loop identification method vs. Open-loop analysis was evaluated. A nonparametric frequency-domain closed-loop identification method was demonstrated for analyzing the dynamic characteristics of the arterial baroreflex system.
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