Studies on the monoexponential nature of the left ventricular pressure fall during isovolumic relaxation period in the diseased heart.

n=47 subjects including normal hearts (n=8) and patients with angina pectoris (n=8), myocardial infarction (n=13), hypertrophic cardiomyopathy (n=10), and dilated cardiomyopathy (n=8).

Measurement of left ventricular pressure (LVP) using a Millar's catheter-tip transducer to derive four types of time constants (T1-T4) during the isovolumic relaxation period.

Normal hearts vs. diseased hearts (angina pectoris, myocardial infarction, hypertrophic cardiomyopathy, dilated cardiomyopathy).

Deviation of left ventricular pressure from the monoexponential curve during the isovolumic relaxation period, assessed by time constants (T1-T4) and constant C.surrogate