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January 1, 1958Thrombosis and Haemostasis

The Stuart-Prower Factor Assay and its Clinical Significance

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Population

Plasma samples for determination of Stuart-Prower factor

Comparison

Modified one-stage test using Russell's viper… vs Specific Stuart-Prower factor assay using…

Design

Other

Authors

FBF BachmannCross-Cutting CardiologyFDF DuckertUniversity of ZurichFKFranz KollerUniversity of Vienna

Discussion

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Implication

May support one-stage Russell's viper venom assay reliability for factor X; leaves open utility in contemporary anticoagulation monitoring.

Structured PICO

P
Population
Plasma samples for determination of Stuart-Prower factor
I
Intervention
Modified one-stage test using Russell's viper venom (Stypven)-cephalin reagent (RVV 1:200,000)
C
Comparator
Specific Stuart-Prower factor assay using patient's plasma deficient in Stuart-Prower factor
O
Outcome
Accuracy and reliability of the assay in detecting Stuart-Prower factor deficienciessurrogate

The described one-stage test using Russell's viper venom is a reliable method for detecting Stuart-Prower factor deficiencies and may aid in monitoring dicoumarol therapy.

Cite This Study

Bachmann et al. (1958) studied this question.

synapsesocial.com/papers/6a7a5399b2ad017e4032237ahttps://doi.org/10.1055/s-0038-1656262
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Russell's Viper Venom (Stypven) on Stuart Clotting Defect1956 · 35 citations
  2. 2An Improved Assay for von Willebrand Factor1979 · 12 citations
  3. 3Improved Distinction of Factor V Wild-Type and Factor V Leiden Using a Novel Prothrombin-Based Activated Protein C Resistance Assay2004 · 26 citations
  4. 4Improved Distinction of Factor V Wild-Type and Factor V Leiden Using a Novel Prothrombin-Based Activated Protein C Resistance Assay2004 · 30 citations
  5. 5An Assessment of an Amidolytic Assay for Factor VII in the Laboratory Control of Oral Anticoagulants1981 · 9 citations