Population
16 patients with idiopathic dilated cardiomyopathy (DCM)
Design
Cross-sectional
Authors
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MMP/TIMP expression may mark remodeling severity in idiopathic DCM; hypothesis-generating, needs longitudinal validation before clinical use.
Expression of MMPs and TIMPs in the cardiac matrix of patients with idiopathic DCM is closely associated with myocardial remodeling and deterioration of LV performance.
Yokoseki et al. (2000) studied this question.
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