Value of intracoronary ultrasound and Doppler in the differentiation of angiographically normal coronary arteries: a prospective study in patients with angina pectoris
Why the study?
Can intracoronary ultrasound and Doppler differentiate underlying pathology in patients with angina pectoris and angiographically normal coronary arteries?
Population
44 patients with suspected coronary artery disease and normal coronary angiograms presenting with angina…
Design
Cohort
Authors
Discussion
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Member takes
Implication
May support intracoronary imaging to detect occult pathology in angina with normal angiograms; hypothesis-generating and should not yet change practice.
Structured PICO
Can intracoronary ultrasound and Doppler differentiate underlying pathology in patients with angina pectoris and angiographically normal coronary arteries?
P
Population
44 patients with suspected coronary artery disease and normal coronary angiograms presenting with angina pectoris
I
Intervention
Intracoronary ultrasound and intracoronary Doppler (with 10 mg papaverine) in the left anterior descending and left main coronary arteries
O
Outcome
Coronary morphology and coronary flow reservesurrogate
Intracoronary ultrasound and Doppler reveal that the majority of patients with angina and normal angiograms have early atherosclerosis or microvascular dysfunction rather than truly normal coronary arteries.
Cite This Study
Erbel et al. (1996) studied this question.