Why the study?
Does sinoaortic denervation prevent postexercise reductions in arterial pressure and cardiac sympathetic tonus in spontaneously hypertensive rats?
Population
Spontaneously hypertensive rats (SHR), n=14 (intact n=9, sinoaortic-denervated n=5)
Comparison
Sinoaortic denervation (SAD) vs Intact (no sinoaortic denervation)
Design
Preclinical
Follow-up
Acute postexercise
Authors
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Supports baroreflex role in postexercise hypotension in SHR models; hypothesis-generating with no immediate clinical implications.
Does sinoaortic denervation prevent postexercise reductions in arterial pressure and cardiac sympathetic tonus in spontaneously hypertensive rats?
The arterial baroreflex is required for the reduction in arterial pressure and cardiac sympathetic tonus that occurs after a single bout of dynamic exercise in spontaneously hypertensive rats.
Chandler et al. (1997) studied this question.
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