Why the study?
Does low-dose colchicine successfully treat recurrent pericarditis in renal transplant patients?
Does low-dose colchicine successfully treat recurrent pericarditis in renal transplant patients?
Low-dose colchicine may be a safe and effective treatment for recurrent pericarditis complicated by tamponade in renal transplant patients.
Answers are grounded in this paper and cite their sources.
Low-dose colchicine may be considered in this rare post-transplant setting; single case leaves open need for prospective confirmation before broader use.
Recurrent pericarditis is a rare complication following renal transplantation. Colchicine, an inhibitor of microtubule polymerization, has been recommended for the treatment of recurrent acute pericarditis in non-transplant patients and is commonly used for the treatment of gout in transplant patients. However, the use of colchicine for the treatment of recurrent pericarditis in renal transplant patients has rarely been reported. In the present study, a rare case of recurrent pericarditis, manifested as large pericardial effusion and pericardial tamponade within the first year following renal transplantation, was successfully treated with colchicine. Therefore, low-dose colchicine may be a safe and effective option for the treatment of recurrent pericarditis in renal transplant patients.
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Gao et al. (2014) studied this question.
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