Key result
Colchicine therapy successfully prevented the recurrence of pericardial effusion over a 6-month follow-up in a patient who had failed conventional therapy after cardiac surgery.
Why the study?
Does colchicine prevent recurrence of pericardial effusion in patients with postsurgical recurrent effusion resistant to conventional therapy?
Case Report (n=1)
No
Does colchicine prevent recurrence of pericardial effusion in patients with postsurgical recurrent effusion resistant to conventional therapy?
Colchicine may be an effective treatment for recurrent pericardial effusion after cardiac surgery when conventional therapy fails.
Answers are grounded in this paper and cite their sources.
May warrant consideration in refractory postsurgical effusion; leaves open confirmation via randomized trials.
Pericardial effusion represents a common postoperative complication in cardiac surgery. Nonetheless, it can be resistant to conventional therapy leading to prolonged in-hospital stay and worsening of clinical conditions. Recent literature shows that colchicine therapy should be useful in the treatment of recurrent post surgical pericardial effusion. Hereby we report the case of a patient with postsurgical recurrent effusion treated with colchicine, and a review of literature concerning the use of this old drug.
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Dainese et al. (2011) conducted a case report in Recurrent pericardial effusion after cardiac surgery (n=1). Colchicine was evaluated on Recurrence of pericardial effusion. Colchicine therapy successfully prevented the recurrence of pericardial effusion over a 6-month follow-up in a patient who had failed conventional therapy after cardiac surgery.
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