Prevention of Recurrent Pericarditis With Colchicine in 2012
Key result
Colchicine therapy effectively prevents recurrent pericarditis, resulting in fewer recurrences and longer symptom-free periods, though pretreatment with corticosteroids attenuates its efficacy.
Why the study?
Does colchicine therapy prevent recurrent pericarditis in patients with pericardial inflammation?
Population
Patients with recurrent pericarditis caused by various etiologies
Comparison
Colchicine therapy vs Other modalities such as corticosteroids and…
Design
Review
Authors
Discussion
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Member takes
Implication
May inform colchicine use in recurrent pericarditis; leaves open prospective validation of steroid attenuation.
Structured PICO
Does colchicine therapy prevent recurrent pericarditis in patients with pericardial inflammation?
P
Population
Patients with recurrent pericarditis caused by various etiologies
I
Intervention
Colchicine therapy
C
Comparator
Other modalities such as corticosteroids and immunosuppressive drugs
O
Outcome
Recurrent pericarditis
Colchicine is a safe and effective modality for the treatment and prevention of recurrent pericarditis, providing sustained benefit superior to other current modalities.
Cite This Study
Markel et al. (2013) conducted a review in Recurrent pericarditis. Colchicine was evaluated on Recurrent pericarditis. Colchicine therapy effectively prevents recurrent pericarditis, resulting in fewer recurrences and longer symptom-free periods, though pretreatment with corticosteroids attenuates its efficacy.