Why the study?
The study was conducted to examine the influence of different hemodynamic parameters on coronary arteries in typical coronary stenosis lesions using dynamic coronary angiography.
A two-way fluid-structure coupling model based on dynamic coronary angiography can accurately simulate coronary hemodynamics with a 6.74% error margin compared to measured FFR.
Patient-specific coronary FFR modeling is feasible; leaves open clinical utility pending larger validation.
In this paper, a two-way fluid-structure coupling model is developed to simulate and analyze the hemodynamic process based on dynamic coronary angiography, and examine the influence of different hemodynamic parameters on coronary arteries in typical coronary stenosis lesions. Using the measured FFR pressure data of a patient, the pressure-time function curve is fitted to ensure the accuracy of the boundary conditions. The average error of the simulation pressure results compared to the test data is 6.74%. In addition, the results related to blood flow, pressure contour and wall shear stress contour in a typical cardiac cycle are obtained by simulation analysis. These results are found to be in good agreement with the laws of the real cardiac cycle, which verifies the rationality of the simulation. In conclusion, based on the modeling and hemodynamic simulation analysis process of dynamic coronary angiography, this paper proposes a method to assist the analysis and evaluation of coronary hemodynamic and functional parameters, which has certain practical significance.
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Yang et al. (2022) studied this question.
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