This review outlines the epidemiology, pathogenesis, and management of diabetic heart disease, highlighting gaps in the evidence base and suggesting future research priorities.
Evidence gaps limit diabetic heart disease management; leaves open optimal strategies pending targeted trials.
Diabetes mellitus is a risk factor for the development of coronary artery disease and chronic heart failure. When carefully screened for, diabetes or prediabetic disorders, are present in the majority of patients with clinically manifest ischaemic heart disease, and confer a major adverse impact upon morbidity and mortality. Important therapeutic modifications are required in the management of coronary artery disease and chronic heart failure associated with diabetes, and vice versa. However, despite optimal management, aided by recent landmark trials solely recruiting patients with diabetes, outcomes for patients with diabetes and heart disease remain poor. This review outlines the epidemiology, pathogenesis and management of diabetic heart disease, along with highlighting the many gaps in the evidence-base and suggesting future research priorities.
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Mercer et al. (2012) studied this question.
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