Why the study?
Does the neutrophil count after reperfusion therapy correlate with infarct size, myocardial tissue-level reperfusion, and LV function in patients with a first anterior wall AMI?
Population
122 consecutive patients with a first anterior wall acute myocardial infarction admitted within 6h of…
Design
Cohort, Outcome assessors were blinded to clinical and angiographic findings.
Follow-up
predischarge
Authors
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Day-2 neutrophil counts may mark reperfusion injury severity in anterior AMI; hypothesis-generating and should not change practice.
Does the neutrophil count after reperfusion therapy correlate with infarct size, myocardial tissue-level reperfusion, and LV function in patients with a first anterior wall AMI?
Neutrophil counts measured on day 2 after reperfusion therapy for anterior AMI correlate more strongly with infarct size and LV function than admission neutrophil counts, suggesting a role for reperfusion-induced inflammation in myocardial damage.
Shinozaki et al. (2005) studied this question.
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