Key result
Higher admission neutrophil counts linked to ~20% greater risk of angiographic no-reflow after STEMI PCI.
Why the study?
The no-reflow phenomenon during primary PCI in STEMI patients leads to poor outcomes, and the relationship between admission neutrophil counts and angiographic no-reflow was unclear.
Do admission neutrophil counts predict angiographic no-reflow in patients with STEMI undergoing primary PCI?
Population
217 patients with acute STEMI undergoing primary PCI
Comparison
No-reflow group vs normal-reflow group based on angiographic findings
Design
Observational cohort study
Authors
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May aid risk stratification for no-reflow in STEMI; hypothesis-generating and requires prospective validation.
Observational (n=217)
Do admission neutrophil counts predict angiographic no-reflow in patients with STEMI undergoing primary PCI?
Odds Ratio: 1.2 (95% CI 1.073–1.342)
p-value: p=0.001
Higher admission neutrophil counts independently predict angiographic no-reflow after primary PCI in STEMI patients, suggesting its utility for early risk stratification.
Wang et al. (2016) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=217). Admission neutrophil counts was evaluated on Angiographic no-reflow (OR 1.200, 95% CI 1.073-1.342, p=0.001). Higher admission neutrophil counts independently predicted angiographic no-reflow following primary percutaneous coronary intervention in patients with STEMI (OR 1.200; 95% CI 1.073-1.342; P=0.001).
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