Key result
Metabolically healthy obesity increased the risk of incident atrial fibrillation (HR 1.6; 95% CI 1.2-2.1) to a similar extent as metabolically unhealthy obesity.
Why the study?
Although atrial fibrillation is associated with obesity and its metabolic consequences, little is known about the association between metabolically healthy obesity and AF.
Does metabolically healthy obesity increase the risk of incident atrial fibrillation compared to metabolically unhealthy obesity?
Cohort (n=47,870)
Does metabolically healthy obesity increase the risk of incident atrial fibrillation compared to metabolically unhealthy obesity?
Hazard Ratio: 1.6 (95% CI 1.2–2.1)
Metabolically healthy obesity increases the risk of incident atrial fibrillation to a similar extent as metabolically unhealthy obesity, indicating that obesity severity drives AF risk regardless of metabolic status.
No takes yet. Share an insight, caveat, or question.
Obese patients warrant AF vigilance regardless of metabolic status; leaves open whether metabolic or weight-focused interventions best mitigate risk.
Feng et al. (2019) conducted a cohort in Atrial fibrillation (n=47,870). Metabolically healthy obesity was evaluated on incident AF (HR 1.6, 95% CI 1.2 to 2.1). Metabolically healthy obesity increased the risk of incident atrial fibrillation (HR 1.6; 95% CI 1.2-2.1) to a similar extent as metabolically unhealthy obesity.