Key result
Whole genome sequencing of 12 Sardinian African swine fever virus isolates demonstrated remarkable genetic stability, supporting a single-source introduction of the virus.
Why the study?
Previous genetic studies of Sardinian African swine fever virus isolates examined only a few selected genes, limiting the ability to distinguish closely related isolates and investigate viral evolution.
Whole genome sequencing of Sardinian ASFV isolates reveals remarkable genetic stability over decades, supporting a single-source introduction.
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Supports targeted genomic surveillance in endemic regions; leaves open drivers of ASFV persistence despite low diversity.
Torresi et al. (2020) studied African swine fever (n=12). Whole genome sequencing vs. 47/Ss/2008 and 26544/OG10 isolates was evaluated on Genetic variations and evolution of ASFV. Whole genome sequencing of 12 Sardinian African swine fever virus isolates demonstrated remarkable genetic stability, supporting a single-source introduction of the virus.
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