Key result
CD2v protein sequencing reveals two temporal Sardinian ASFV subgroups to track viral spread.
Population
African swine fever virus isolates from Sardinia collected over a 13-year period and various strains from…
Design
Preclinical
Authors
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May support ASFV surveillance in swine; leaves open validation as a global genetic marker.
Observational
The cytoplasmic region of the CD2v protein can serve as a new genetic marker to analyze African swine fever viruses from different locations and track virus spread.
Sanna et al. (2016) conducted an observational in African swine fever virus (ASFV). Sequence analysis of p30, CD2V, and I73R/I329L variable regions was evaluated on Genetic variability and temporal subdivision of Sardinian ASFV isolates. Sequence analysis of the CD2v protein revealed a temporal subdivision of Sardinian ASFV isolates into two subgroups (1978-1990 and 1990-2014), proposing it as a new genetic marker to track virus spread.
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