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February 1, 2002Coronary Artery Disease

The prevalence of impaired left ventricular diastolic filling is related to the extent of coronary atherosclerosis in patients with stable coronary artery disease

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Why the study?

Is the extent of coronary atherosclerosis associated with impaired left ventricular diastolic filling in patients with stable coronary artery disease?

Population

170 consecutive patients with stable coronary artery disease (CAD) and an abnormal coronary angiogram

Design

Cross-sectional

Authors

ERErik RydbergLund UniversityRWRonnie WillenheimerHeart Failure & TransplantLELeif ErhardtHeart Failure & Transplant

Discussion

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Implication

Impaired diastolic filling tracks with CAD extent in stable patients; hypothesis-generating for causality and clinical relevance pending prospective data.

Structured PICO

Is the extent of coronary atherosclerosis associated with impaired left ventricular diastolic filling in patients with stable coronary artery disease?

P
Population
170 consecutive patients with stable coronary artery disease (CAD) and an abnormal coronary angiogram
O
Outcome
Prevalence of impaired left ventricular diastolic filling (defined as E/A ≤0.75, or E/A >1.0 combined with S/D ≤1.0)surrogate

In patients with stable CAD, the prevalence of impaired LV diastolic filling is high (41%) and correlates independently with the angiographic extent of coronary atherosclerosis.

Cite This Study

Rydberg et al. (2002) studied this question.

synapsesocial.com/papers/6a7b481677336a1bae032205https://doi.org/10.1097/00019501-200202000-00001

Topics

Coronary artery diseaseWomen and heart disease
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Also Consider

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  1. 1Systolic and Diastolic Abnormalities of the Left Ventricle in Coronary Artery Disease1970 · 165 citations
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  5. 5The stunned myocardium: prolonged, postischemic ventricular dysfunction.1982 · 2,819 citations