Why the study?
Elevated gradients are proposed to associate with haemodynamic structural valve deterioration after TAVI, but data regarding their characterisation remain scarce.
Population
691 patients undergoing transfemoral TAVI
Follow-up
12-month
Key result
Haemodynamic structural valve deterioration occurred in 10.3% of patients 12 months post-TAVI, with oral anticoagulation (RR 8.65) and valve-in-valve procedures (RR 52.76) as significant predictors.
Authors
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May warrant closer post-TAVI surveillance in patients on OAC or with valve-in-valve; hypothesis-generating, needs confirmation before practice change.
Observational (n=691)
Relative Risk: 8.65
p-value: p=0.004 for OAC; <0.001 for valve-in-valve
Haemodynamic structural valve deterioration occurs in approximately 10% of patients within 12 months after TAVI with balloon-expandable valves, with valve-in-valve procedures and oral anticoagulation identified as significant predictors.
Rheude et al. (2020) conducted an observational in Transcatheter aortic valve implantation (TAVI) (n=691). Oral anticoagulation and valve-in-valve procedure was evaluated on Moderate or severe haemodynamic structural valve deterioration (SVD) during 12-month follow-up (RR 8.65 for OAC; RR 52.76 for valve-in-valve, p=0.004 for OAC; <0.001 for valve-in-valve). Haemodynamic structural valve deterioration occurred in 10.3% of patients 12 months post-TAVI, with oral anticoagulation (RR 8.65) and valve-in-valve procedures (RR 52.76) as significant predictors.