Key result
Abnormal LV non-systolic function during CAB was associated with a longer median hospital stay (9.1 vs 6.5 days, P<0.001) and a lower probability of discharge (HR 0.66; 95% CI 0.47-0.93).
Why the study?
Whether abnormal left ventricular echocardiographic parameters during the non-systolic phase are associated with the duration of hospital stay after coronary artery bypass surgery was unknown.
Does abnormal left ventricular non-systolic function predict prolonged length of hospital stay in patients with normal systolic function undergoing coronary artery bypass graft?
Observational
No
Does abnormal left ventricular non-systolic function predict prolonged length of hospital stay in patients with normal systolic function undergoing coronary artery bypass graft?
Hazard Ratio: 0.66 (95% CI 0.47–0.93)
Absolute Event Rate: 9.1% vs 6.5%
p-value: p=< 0.001
Intra-operative identification of non-systolic LV dysfunction in patients with normal systolic function undergoing CABG predicts a significantly prolonged postoperative hospital stay.
Non-systolic LV abnormalities may prolong post-CAB stay; hypothesis-generating and requires prospective validation before guiding care.
Background: Abnormal left ventricular (LV) echocardiographic parameters during non-systolic phase, with or without a diagnosis of heart failure, is a common finding that can be easily diagnosed by intra-operative transesophageal echocardiography (TEE). However, its association with duration of hospital stay after coronary artery bypass (CAB) is unknown. Objective: To determine if Abnormal left ventricular (LV) echocardiographic parameters during non-systolic phase is associated with length of hospital stay after coronary artery bypass surgery (CAB). Method: Prospective observational study at a single tertiary academic medical center Result: Median time to hospital discharge was significantly longer for subjects with abnormal left ventricular (LV) echocardiographic parameters during non-systolic phase (9.1/IQR 6.6-13.5 days) than those with normal LV non-systolic function (6.5/IAR 5.3-9.7days) (P< 0.001). The probability of hospital discharge was 34% lower (HR 0.66/95% CI 0.47-0.93) for subjects with abnormal LV function even during non-systole despite a normal LV systolic function, independent of potential confounders, including a baseline diagnosis of heart failure Conclusions and Relevance: In patients with normal systolic function undergoing CAB, non-systolic LV dysfunction is associated with prolonged duration of postoperative hospital stay. This association cannot be explained by baseline comorbidities or common post-operative complications.
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Mondal et al. (2021) conducted an observational in Coronary artery bypass surgery (CAB). Abnormal left ventricular (LV) echocardiographic parameters during non-systolic phase vs. Normal LV non-systolic function was evaluated on Length of hospital stay after coronary artery bypass surgery (HR 0.66, 95% CI 0.47-0.93, p=< 0.001). Abnormal LV non-systolic function during CAB was associated with a longer median hospital stay (9.1 vs 6.5 days, P<0.001) and a lower probability of discharge (HR 0.66; 95% CI 0.47-0.93).
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