Population
mdx and control mice aged between 26 and 350 days
Comparison
mdx mouse model vs age-matched control mice
Design
Preclinical
Authors
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May inform age-specific DMD modeling; leaves open translation of mdx force data to patients.
The mdx mouse model exhibits age-dependent changes in muscle size and strength, with older muscles showing considerable regenerative capacity.
Coulton et al. (1988) studied this question.
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