Key result
The microcirculation plays a central role in the pathophysiology of cardiovascular disease, target organ damage, and the control of vascular resistance in conditions such as hypertension.
The microcirculation plays a central role in the pathophysiology of cardiovascular disease, target organ damage, and the control of vascular resistance.
Supports microcirculation assessment in hypertension; leaves open whether targeted interventions improve outcomes.
T he role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease. The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidney. Both functional and structural alterations in the small arteries, arterioles, and capillaries are the basis of target organ damage. Furthermore, the microcirculation is the major site of control of vascular resistance. This makes it a central player in the etiopathogenesis of diseases characterized by an increased vascular resistance, such as hypertension.
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Struijker-Boudier et al. (2012) conducted a review in Cardiovascular disease. The microcirculation plays a central role in the pathophysiology of cardiovascular disease, target organ damage, and the control of vascular resistance in conditions such as hypertension.
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