⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

June 28, 2005CirculationOpen Access

Defective Ryanodine Receptor Interdomain Interactions May Contribute to Intracellular Ca 2+ Leak

View Full Paper

Ask AI

Bookmark

Share

Authors

SLStephan E. LehnartElectrophysiology XWXander H.T. WehrensElectrophysiology AMAndrew R. MarksElectrophysiology

Discussion

Loading...

Member takes

Implication

May support SNS-targeted interventions in advanced HF; leaves open optimal strategies in contemporary practice.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Lehnart et al. (2005) studied this question.

synapsesocial.com/papers/6a7baaec84d0f3193c75e2de https://doi.org/10.1161/circulationaha.105.551861

Topics

Heart failure HFrEF treatment Heart failure hospitalization

View Full Paper

Ask AI

Bookmark

Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts1982 · 2,284 citations
2Protein Kinase A Phosphorylation of the Cardiac Calcium Release Channel (Ryanodine Receptor) in Normal and Failing Hearts2002 · 208 citations
3FKBP12.6-Mediated Stabilization of Calcium-Release Channel (Ryanodine Receptor) as a Novel Therapeutic Strategy Against Heart Failure2003 · 263 citations
4PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle2003 · 245 citations
5Postulated Role of Interdomain Interaction within the Ryanodine Receptor in Ca2+ Channel Regulation2000 · 127 citations