Why the study?
Do hyperglycemia and current cigarette smoking increase the risk of onset of microalbuminuria in patients with type 1 diabetes?
Population
943 patients aged 15-44 years with type 1 diabetes who had normoalbuminuria during the 2-year baseline period
Comparison
Hyperglycemia and current cigarette smoking vs Lower HbA1c levels and past or never smoking
Design
Cohort
Follow-up
4 years
Authors
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HbA1c >8% and current smoking were associated with higher microalbuminuria incidence in type 1 diabetes; leaves open whether targeted modification prevents onset.
Do hyperglycemia and current cigarette smoking increase the risk of onset of microalbuminuria in patients with type 1 diabetes?
In patients with type 1 diabetes, current smoking and HbA1c levels >8% are major, synergistic determinants for the onset of microalbuminuria.
Scott et al. (2001) studied this question.
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