Key result
Cigarette smoking was associated with a 2.8 times higher prevalence of increased albumin excretion rates compared to nonsmokers in young subjects with type I diabetes.
Why the study?
Does cigarette smoking increase the risk of albuminuria and retinopathy in young subjects with type 1 diabetes?
Population
359 young subjects with insulin-dependent diabetes mellitus (type 1 diabetes)
Comparison
Cigarette smoking vs Non-smoking
Design
Cohort
Authors
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Supports smoking cessation counseling in young type 1 diabetes; hypothesis-generating for albuminuria progression and requires prospective confirmation.
Observational (n=359)
Does cigarette smoking increase the risk of albuminuria and retinopathy in young subjects with type 1 diabetes?
Relative Risk: 2.8
Cigarette smoking is an independent risk factor for the development and progression of early diabetic renal damage (albuminuria) and worsening of retinal disease in young subjects with type 1 diabetes.
H. Peter Chase (1991) conducted an observational in Type I diabetes (n=359). Cigarette smoking vs. Nonsmokers was evaluated on Increased albumin excretion rates (2.8 times higher). Cigarette smoking was associated with a 2.8 times higher prevalence of increased albumin excretion rates compared to nonsmokers in young subjects with type I diabetes.
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