Key result
Microalbuminuria was associated with a 42% increased risk of progression to overt nephropathy compared to normoalbuminuria (OR 1.42; 95% CI 0.98-2.06).
Why the study?
Does microalbuminuria predict progression to overt nephropathy in patients with type 2 diabetes?
Population
1,253 type 2 diabetic patients, mean age 68.4 years, mean disease duration 10.4 years, from Casale…
Comparison
Microalbuminuria and other baseline risk factors vs Normoalbuminuria
Design
Cohort
Follow-up
median 5.33 years
Authors
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May aid nephropathy risk assessment in type 2 diabetes; hypothesis-generating for independent prediction.
Cohort (n=1,253)
No
Does microalbuminuria predict progression to overt nephropathy in patients with type 2 diabetes?
Odds Ratio: 1.42 (95% CI 0.98–2.06)
Microalbuminuria, along with HbA1c, HDL cholesterol, apolipoprotein B, and fibrinogen, predicts progression to overt nephropathy in patients with type 2 diabetes.
Bruno et al. (2003) conducted a cohort in Type 2 diabetes (n=1,253). Microalbuminuria vs. Normoalbuminuria was evaluated on Progression to overt nephropathy (OR 1.42, 95% CI 0.98-2.06). Microalbuminuria was associated with a 42% increased risk of progression to overt nephropathy compared to normoalbuminuria (OR 1.42; 95% CI 0.98-2.06).
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