Why the study?
Does vertebral injection of angiotensin II produce a different systemic arterial pressure and heart rate response compared to aortic injection in humans?
Does vertebral injection of angiotensin II produce a different systemic arterial pressure and heart rate response compared to aortic injection in humans?
Vertebral injection of angiotensin II in humans causes a rise in blood pressure partly by increasing sympathetic nerve activity, demonstrating a centrally mediated vasopressor effect.
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Suggests central sympathetic contribution to angiotensin II pressor effects; leaves open clinical relevance in human hypertension.
UEDA et al. (1969) studied this question.
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