Why the study?
Does atropine alter left ventricular volumes and ejection and filling rates at rest and during exercise in healthy young men?
Does atropine alter left ventricular volumes and ejection and filling rates at rest and during exercise in healthy young men?
Atropine-induced parasympathetic blockade increases heart rate and cardiac output but decreases stroke volume and left ventricular volumes, demonstrating that parasympathetic tone contributes to left ventricular dilatation and enhancement of ejection.
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Atropine augments resting hemodynamics in healthy men; hypothesis-generating for parasympathetic LV modulation, needs confirmation in patients and exercise.
Kelbæk et al. (1991) studied this question.
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