Why the study?
Does intravenous atropine affect autonomic indices based on electrocardiographic R-R intervals in healthy volunteers?
Population
10 healthy volunteers
Comparison
Cumulative doses of atropine vs Equivalent volumes of water for injection
Design
Other
Authors
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Respiratory ratio may selectively index resting vagal tone; leaves open the parasympathetic basis of Valsalva ratio in patients.
Does intravenous atropine affect autonomic indices based on electrocardiographic R-R intervals in healthy volunteers?
The resting vagal tone can be selectively measured using the respiratory ratio, while the Valsalva ratio is unlikely to be closely related to parasympathetic control of the heart.
Julu et al. (1992) studied this question.
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