Key result
High maternal BMI in early pregnancy and higher gestational weight gain were independently associated with worse maternal hemodynamic and vascular indices at 35-37 weeks' gestation.
Why the study?
Obese pregnant women face increased risks of adverse pregnancy outcomes and premature cardiovascular disease, but the associated maternal hemodynamic and vascular alterations remain incompletely understood.
Is increased maternal BMI and gestational weight gain associated with worse maternal hemodynamic and vascular parameters at 35-37 weeks' gestation?
Population
Pregnant women assessed at 35-37 weeks' gestation
Comparison
Overweight or obese women vs normal-weight women across gestational weight gain
Design
Observational cohort study
Authors
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May inform early-pregnancy weight counseling; extends observational data on maternal hemodynamics but should not yet change practice.
Observational
Is increased maternal BMI and gestational weight gain associated with worse maternal hemodynamic and vascular parameters at 35-37 weeks' gestation?
Higher maternal BMI in early pregnancy and greater gestational weight gain are independently associated with adverse maternal hemodynamic and vascular alterations in late pregnancy.
Charakida et al. (2025) conducted an observational in Pregnancy. High maternal BMI and gestational weight gain vs. Normal-weight women was evaluated on Maternal hemodynamic and vascular indices (including blood pressure, cardiac output, aortic stiffness, and UtA-PI). High maternal BMI in early pregnancy and higher gestational weight gain were independently associated with worse maternal hemodynamic and vascular indices at 35-37 weeks' gestation.
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