Why the study?
Are there differentially expressed microRNAs in the heart tissues of patients with ARVC compared to healthy controls?
Population
24 ARVC patients heart samples and 24 healthy controls
Comparison
MicroRNA expression profiling using S-Poly Plus… vs Healthy controls
Design
Case-control
Authors
Loading...
These signatures warrant validation as ARVC biomarkers; leaves open their role as therapeutic targets in Wnt/Hippo pathways.
Are there differentially expressed microRNAs in the heart tissues of patients with ARVC compared to healthy controls?
Identification of 21 microRNA signatures in ARVC highlights miR-21-5p and miR-135b as potential therapeutic targets linked to Wnt and Hippo pathways.
Zhang et al. (2016) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: