May 1, 1989HypertensionOpen Access

Cardiovascular regulatory functions in elderly patients with hypertension.

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Why the study?

Does hypertension alter cardiovascular regulatory functions independently of aging in elderly patients?

Population

72 subjects in total: 30 elderly hypertensive patients, 30 healthy elderly normotensive volunteers, and 12…

Design

Cross-sectional

Authors

AKAtsuhiko KawamotoFoundation for Biomedical Research KSKazuyuki ShimadaNihon University KMKozo MatsubayashiKyoto University

Discussion

Member takes

Implication

Hypertension may independently alter hemodynamics beyond aging effects in the elderly; leaves open whether these associations warrant targeted interventions.

Structured PICO

Does hypertension alter cardiovascular regulatory functions independently of aging in elderly patients?

Population

72 subjects in total: 30 elderly hypertensive patients (World Health Organization stages I and II, mean age 66 years), 30 healthy elderly normotensive volunteers (mean age 65 years), and 12 young normotensive subjects (mean age 23 years).

Comparator

Healthy elderly normotensive volunteers and young normotensive subjects

Outcome

Resting hemodynamic measurements and circulatory autonomic functions (including cardiac index, total peripheral resistance, beta-receptor sensitivity, baroreceptor reflex sensitivity, heart rate variability, and plasma biomarkers)surrogate

Hypertension in the elderly primarily affects resting hemodynamics (cardiac index and peripheral resistance), whereas aging itself is the primary driver of depressed circulatory autonomic functions.

Cite This Study

Kawamoto et al. (1989) studied this question.

synapsesocial.com/papers/6a7bf16c073f483584dfa3bc https://doi.org/10.1161/01.hyp.13.5.401

Topics

Hypertension management

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Implication

Hypertension may independently alter hemodynamics beyond aging effects in the elderly; leaves open whether these associations warrant targeted interventions.

Cardiovascular regulatory functions in elderly patients with hypertension.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Cardiovascular regulatory functions in elderly patients with hypertension.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider