September 1, 1994Artificial Organs
Chaotic Hemodynamics During Oscillated Blood Flow
Population
Adult goats (animal model for artificial heart system)
Comparison
Vibrating flow pump generating oscillated blood… vs Natural circulation
Design
Preclinical
Authors
Discussion
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Member takes
Implication
May require cautious parameter tuning in preclinical pump development; leaves open translation to human circulatory support.
Structured PICO
P
Population
Adult goats (animal model for artificial heart system)
I
Intervention
Vibrating flow pump (VFP) generating oscillated blood flow (10-50 Hz/min) implanted between the left atrium and aorta (ascending aorta clamped)
C
Comparator
Natural circulation
O
Outcome
Hemodynamic patterns analyzed via nonlinear mathematical techniques (phase portrait, Lyapunov exponent)surrogate
Oscillated blood flow from a vibrating flow pump creates a lower dimensional homeochaotic hemodynamic state, indicating that hemodynamic parameters require careful regulation against unexpected external stimuli.
Cite This Study
Yambe et al. (1994) studied this question.