Why the study?
Does moderate-intensity exercise at progressively increasing high altitude affect hs-cTnT levels and cardiac function in healthy subjects?
Population
19 healthy subjects, mean age 35.4 years, 52.6% male
Comparison
Moderate-intensity progressive trekking to high… vs Baseline measurements at rest at 1300 m
Design
Cohort
Follow-up
Duration of the trek to 5150 m
Authors
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Moderate-altitude exercise may elevate hs-cTnT via hemodynamic and hypoxic stress; hypothesis-generating and should not yet change practice.
Does moderate-intensity exercise at progressively increasing high altitude affect hs-cTnT levels and cardiac function in healthy subjects?
Moderate intensity exercise at significant high altitude increases hs-cTnT levels, driven by changes in cardiac output, right ventricular pressure, and hypoxia, without overt deleterious effects on cardiac function.
Mellor et al. (2013) studied this question.
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