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July 1, 1987IEEE Transactions on Biomedical Engineering

Periodic Conductivity as a Mechanism for Cardiac Stimulation and Defibrillation

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Population

Periodic strand of cardiac muscle (theoretical/computational model)

Comparison

Extracellular stimulation, defibrillation… vs Continuous fiber model

Design

Preclinical

Authors

WKWanda KrassowskaTPT.C. PilkingtonRIRaymond E. Ideker

Discussion

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Overview

Hypothesis-generating for discrete fiber models in defibrillation; leaves open clinical translation beyond animal preparations.

Structured PICO

P
Population
Periodic strand of cardiac muscle (theoretical/computational model)
I
Intervention
Extracellular stimulation, defibrillation, intracellular stimulation, and action potential propagation
C
Comparator
Continuous fiber model
O
Outcome
Distribution of the transmembrane potential

The periodic component of transmembrane potential in discrete cardiac muscle structures may explain the mechanism of depolarization and defibrillation during extracellular stimulation.

Cite This Study

Krassowska et al. (1987) studied this question.

synapsesocial.com/papers/6a7c0bf20449e558d7c2c9f7https://doi.org/10.1109/tbme.1987.325986
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Potential distribution in three-dimensional periodic myocardium. II. Application to extracellular stimulation1990 · 59 citations
  2. 2The role of cardiac tissue structure in defibrillation1998 · 141 citations
  3. 3Models of defibrillation of cardiac tissue1998 · 58 citations
  4. 4Mechanism of Ventricular Defibrillation2000 · 38 citations
  5. 5Electrical stimulation of cardiac tissue: a bidomain model with active membrane properties1994 · 112 citations