Why the study?
Non-invasive assessment of LV filling pressure is pivotal in SSc, but the utility of LA stiffness had never been investigated in this population.
Does left atrial stiffness better predict elevated NT-proBNP levels compared to LA volume and strain parameters in patients with systemic sclerosis?
Does left atrial stiffness better predict elevated NT-proBNP levels compared to LA volume and strain parameters in patients with systemic sclerosis?
Left atrial stiffness is superior to LA volume and reservoir strain in predicting elevated NT-proBNP levels, suggesting its utility in identifying HFpEF in systemic sclerosis patients.
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LA stiffness may aid non-invasive LV filling pressure assessment in SSc-HFpEF; leaves open its added value over LA volume and strain.
Porpáczy et al. (2019) studied this question.
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