Why the study?
PCI in very small vessel coronary arteries is challenging because of adverse short-term and long-term outcomes.
Does 2.25 mm drug-eluting stent implantation provide favorable 1-year clinical outcomes in Indian patients with symptomatic very small-calibre coronary artery disease?
Does 2.25 mm drug-eluting stent implantation provide favorable 1-year clinical outcomes in Indian patients with symptomatic very small-calibre coronary artery disease?
Implantation of 2.25 mm drug-eluting stents in very small coronary artery lesions demonstrated favorable 1-year clinical outcomes with a low MACE rate of 3.0% in an Indian population.
DES feasible in very small vessels among Indian patients; leaves open need for randomized trials to confirm outcomes.
Percutaneous coronary intervention (PCI) in very small vessel coronary arteries is challenging due to adverse short-term as well as long-term outcomes. This single-arm, open-label, observational study assessed 1-year clinical outcomes of drug-eluting stents (DES) in Indian patients undergoing PCI for symptomatic very small-calibre coronary artery disease. It enrolled 66 Indian patients with 74 very small coronary artery lesions (reference vessel diameter: ≥2.0 and ≤ 2.25 mm); eligible for implantation with 2.25 mm DES. The primary endpoint of major adverse cardiovascular events (MACE) was 3.0% indicating favourable 1-year clinical outcomes of DES in very small coronary artery lesions in Indian patients.
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Hardas et al. (2021) studied this question.
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